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Brown SM, Campbell LT, Lodge JK.
Cryptococcus neoformans, a fungus under stress.
Curr Opin Microbiol. 2007 Aug;10(4):320-5.
Baker LG,
Specht CA, Donlin MJ, Lodge JK.
Chitosan, the Deacetylated Form of Chitin, Is Necessary for Cell Wall
Integrity
in Cryptococcus neoformans.
Eukaryot Cell. 2007 May;6(5):855-67.
Goins CL, Gerik KJ, Lodge JK.
Improvements to gene deletion in the fungal pathogen Cryptococcus neoformans:
absence of Ku proteins increases homologous recombination, and co-transformation
of independent DNA molecules allows rapid complementation of deletion
phenotypes.
Fungal Genet Biol. 2006 Aug;43(8):531-44.
Missall TA, Pusateri ME, Donlin MJ, Chambers
KT, Corbett JA, Lodge JK.
Posttranslational, translational, and transcriptional responses to nitric
oxide
stress in Cryptococcus neoformans: implications for virulence.
Eukaryot Cell. 2006 Mar;5(3):518-29.
Tang RJ, Breger J, Idnurm A, Gerik KJ, Lodge
JK, Heitman J, Calderwood SB, Mylonakis E.
Cryptococcus neoformans gene involved in mammalian pathogenesis identified
by a
Caenorhabditis elegans progeny-based approach.
Infect Immun. 2005 Dec;73(12):8219-25.
Banks IR, Specht CA, Donlin MJ, Gerik KJ, Levitz
SM, Lodge JK.
A chitin synthase and its regulator protein are critical for chitosan
production and growth of the fungal pathogen Cryptococcus neoformans.
Eukaryot Cell. 2005 Nov;4(11):1902-12.
Gerik KJ, Donlin MJ, Soto CE, Banks AM, Banks
IR, Maligie MA, Selitrennikoff CP, Lodge JK.
Cell wall integrity is dependent on the PKC1 signal transduction pathway
in
Cryptococcus neoformans.
Mol Microbiol. 2005 Oct;58(2):393-408.
Missall TA, Cherry-Harris JF, Lodge JK.
Two glutathione peroxidases in the fungal pathogen Cryptococcus neoformans
are
expressed in the presence of specific substrates.
Microbiology. 2005 Aug;151(Pt 8):2573-81.
Missall TA, Lodge JK.
Function of the thioredoxin proteins in Cryptococcus neoformans during
stress
or virulence and regulation by putative transcriptional modulators.
Mol Microbiol. 2005 Aug;57(3):847-58.
Missall TA, Lodge JK.
Thioredoxin reductase is essential for viability in the fungal pathogen
Cryptococcus neoformans.
Eukaryot Cell. 2005 Feb;4(2):487-9.
Loftus BJ, Fung E, Roncaglia P, Rowley D, Amedeo
P, Bruno D, Vamathevan J,
Miranda M, Anderson IJ, Fraser JA, Allen JE, Bosdet IE, Brent MR, Chiu
R,
Doering TL, Donlin MJ, D'Souza CA, Fox DS, Grinberg V, Fu J, Fukushima
M, Haas
BJ, Huang JC, Janbon G, Jones SJ, Koo HL, Krzywinski MI, Kwon-Chung JK,
Lengeler
KB, Maiti R, Marra MA, Marra RE, Mathewson CA, Mitchell TG, Pertea M,
Riggs FR,
Salzberg SL, Schein JE, Shvartsbeyn A, Shin H, Shumway M, Specht CA, Suh
BB,
Tenney A, Utterback TR, Wickes BL, Wortman JR, Wye NH, Kronstad JW, Lodge
JK,
Heitman J, Davis RW, Fraser CM, Hyman RW.
The genome of the basidiomycetous yeast and human pathogen Cryptococcus
neoformans.
Science. 2005 Feb 25;307(5713):1321-4.
Missall TA, Moran JM, Corbett JA, Lodge JK.
Distinct stress responses of two functional laccases in Cryptococcus neoformans
are revealed in the absence of the thiol-specific antioxidant Tsa1.
Eukaryot Cell. 2005 Jan;4(1):202-8.
Tenney AE, Brown RH, Vaske C, Lodge JK, Doering TL,
Brent MR.
Gene prediction and verification in a compact genome with numerous small
introns.
Genome Res. 2004 Nov;14(11):2330-5.
Missall TA, Lodge JK, McEwen JE.
Mechanisms of resistance to oxidative and nitrosative stress: implications
for
fungal survival in mammalian hosts.
Eukaryot Cell. 2004 Aug;3(4):835-46.
Missall TA, Pusateri ME, Lodge JK.
Thiol peroxidase is critical for virulence and resistance to nitric oxide
and
peroxide in the fungal pathogen, Cryptococcus neoformans.
Mol Microbiol. 2004 Mar;51(5):1447-58.
Nelson, R.T., Pryor, B., and Lodge, J.K.
Sequence length required for homologous recombination in Cryptococcus
neoformans.
Fungal Genetics and Biology. 2003 Feb; 38: 1-9
Nelson, R.T., Hua, J., Pryor, B., and Lodge, J.K.
Identification of virulence mutants of the fungal pathogen, Cryptococcus
neoformans using signature tagged mutagenesis.
Genetics 157:935-947, 2001.
Heitman, J., Casadevall, A., Lodge, J. K. and Perfect,
J. R.
The Cryptococcus neoformans genome sequencing project. (2000)
Mycopathologia 148: 1-7, 2000.
Hua J, Meyer JD, Lodge JK: Development of positive
selectable markers for use in the fungal pathogen Cryptococcus neoformans.
Clin Diagn Lab Immunol. 7:125-127, 2000.
Lodge JK, Jackson-Machelski E, Higgins M, Devadas B,
McWherter CA, Gordon JI: Genetic and biochemical studies establish that
the fungicidal effect of a fully depeptidized inhibitor of Cryptococcus
neoformans myristoylCoA:protein N-myristoyltransferase is Nmt dependent.
J Biol Chem. 273:12482-12491, 1998.
Devadas B, Freeman SK, McWherter CA, Kishore NS, Lodge
JK, Jackson-Machelski E, Gordon JI, SikorskiJA: Novel biologically active
nonpeptidic inhibitors of Myristoyl-CoA:Protein N-myristoyltransferase
(Nmt). J Med Chem. 41:996-1000, 1998.
Lodge JK, Jackson-Machelski E, Devadas B, Zupec ME,
Getman DP, Kishore N, Freeman SK, McWherter CA, Sikorski JA, Gordon JI:
N-myristoylation of Arf proteins in Candida albicans: an in vivo assay
for evaluating antifungal inhibitors of myristoylCoA:protein N-myristoyltransferase.
Microbiology 143:357-366,1997.
Lodge JK, Jackson-Machelski E, Toffaletti DL, Perfect
JR, Gordon JI: Targeted gene replacement demonstrates that myristoylCoA:protein
N-myristoyltransferase is essential for the viability of Cryptococcus
neoformans. Proc Natl Acad Sci USA 91:12008-12012, 1994.
Lodge JK, Gordon JI: Isolation and characterization
of genes encoding myristoylCoA:protein N-myristoyltranferase (Nmt) and
one of its principal substrates, ADP-ribosylation factor (Arf), from Cryptococcus
neoformans and Histoplasma capsulatum. In Molecular Biology of Pathogenic
Fungi: A Laboratory Manual (Maresca B, Kobayashi GS Eds.), pp. 413-431,
Telos Press, New York, NY, 1994.
Lodge JK, Johnson
RL, Weinberg RA, Gordon JI: Comparison of myristoylCoA:protein N-myristoyltransferases
from three pathogenic fungi - Cryptococcus neoformans, Histoplasma
capsulatum and Candida albicans. J Biol Chem. 269:2996-3009,
1994.
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