Ángel Baldán, Ph.D.
Studies on sterol homeostasis and the molecular mechanisms involved in the conversion of macrophages to foam cells.
Office: DRC, Room 615
Phone: (314) 977-9227
Ph.D., 2002, University of Barcelona
Our laboratory is interested in sterol homeostasis and in the molecular mechanisms involved in the conversion of macrophages into foam cells. This latter process is particularly relevant in several human pathologies, including atherosclerosis and different pulmonary lipidosis syndromes.
- miRNAs and high-density lipoprotein metabolism.
Baldan A and de Aguiar Vallim TQ. Biochim Biophys Acta. (2016) pii: S1388.
- miR-27b inhibits LDLR and ABCA1 expression but does not influence plasma and hepatic lipid levels in mice.
Goedecke L, Rotllan N, et al. Atherosclerosis. (2015) 243(2):499-509.
- Akt-mediated FoxO1 inhibition is required for liver regeneration.
Pauta M, Rotllan N, et al. Hepatology. (2015) 63(5):1660-1674.
- CIDEC/FSP27 is regulated by peroxisome proliferator-activated receptor alpha and plays a critical role in fasting- and diet-induced hepatosteatosis.
Langhi C, Baldán A. Hepatology. (2015) 61(4):1227-1238.