Education
Ph.D., 1982, University of North Carolina, Chapel Hill
Research Interests
Research in my lab concerns four aspects of transcriptional regulation: histone biotinylation and gene expression; transcriptional activation and chromatin remodeling; RNA polymerase elongation factors and gene regulation; and heterochromatin and gene regulation. We use the fruit fly, Drosophila melanogaster, as a model to study mechanisms of gene activation and gene silencing.
Recent Publications
  • The Nobel path of cellular proteins.
    Eisenberg JC, Sly WS. Mo Med. (2014) 111:114-119.
  • Epigenetics: modifying the genetic blueprint.
    Eisenberg JC. Mo Med. (2014) 111:428-433.
  • Histone H3 lysine-to-methionine mutants as a paradigm to study chromatin signaling.
    Herz, H-M, Morgan M, et al. Science. (2014) 345(6200):1065-1070.
  • HP1a: A structural chormosomal protein regulating transcription.
    Eissenberg JC, Elgin SC. Trends Genet. (2014) 30(3):103-110.
  • Polyphosphate amplifies proinflammatory responses of nuclear proteins through interaction with receptor for advanced glycation end products and P2Y1 purinergic receptor.
    Dinarvand P, Hassanian SM, et al. Blood. (2013) 123(6):935-945.
  • Seed and soil: A conceptual framework of metastasis for clinicians.
    Faraji F, Eissenberg JC. Mo Med. (2013) 110(4):302-308.
  • In vitro veritas: 90 years of biochemistry at Saint Louis University.
    Eissenberg JC, Di Cera E. Mo Med. (2013) 110(4):297-301.
  • The little elongation complex functions at initiation and elongation phases of snRNA gene transcription.
    Hu D, Smith ER, et al. Mol Cell. (2013) 51(4):493-505.
  • Telomeres, cancer & aging: Live long & prosper?
    Eissenberg JC. Mo Med. (2013) 110(1):11-6.