Joel Eissenberg, Ph.D.
Professor and Associate Dean for Research
Mechanisms of gene activation and gene silencing as well as aspects of transcriptional regulation using Drosophila as a model system.
Office: DRC, Room 421
Voice: (314) 977-9235
Ph.D., 1982, University of North Carolina, Chapel Hill
Research in my lab concerns four aspects of transcriptional regulation: histone biotinylation and gene expression; transcriptional activation and chromatin remodeling; RNA polymerase elongation factors and gene regulation; and heterochromatin and gene regulation. We use the fruit fly, Drosophila melanogaster, as a model to study mechanisms of gene activation and gene silencing.
- (2014) Histone H3 lysine-to-methionine mutants as a paradigm to study chromatin signaling.
Herz, H-M, Morgan M, et al. Science. (2014) 345(6200):1065-1070.
- HP1a: A structural chormosomal protein regulating transcription.
Eissenberg JC, Elgin SC. Trends Genet. (2014) 30(3):103-110.
- Polyphosphate amplifies proinflammatory responses of nuclear proteins through interaction with receptor for advanced glycation end products and P2Y1 purinergic receptor.
Dinarvand P, Hassanian SM, et al. Blood. (2013) 123(6):935-945.
- Seed and soil: A conceptual framework of metastasis for clinicians.
Faraji F, Eissenberg JC. Mo Med. (2013) 110(4):302-308.
- In vitro veritas: 90 years of biochemistry at Saint Louis University.
Eissenberg JC, Di Cera E. Mo Med. (2013) 110(4):297-301.
- The little elongation complex functions at initiation and elongation phases of snRNA gene transcription.
Hu D, Smith ER, et al. Mol Cell. (2013) 51(4):493-505.
- Telomeres, cancer & aging: Live long & prosper?
Eissenberg JC. Mo Med. (2013) 110(1):11-6.