Joel Eissenberg, Ph.D.
Professor and Associate Dean for Research
Mechanisms of gene activation and gene silencing as well as aspects of transcriptional regulation using Drosophila as a model system.
Office: DRC, Room 421
Phone: (314) 977-9235
Ph.D., 1982, University of North Carolina, Chapel Hill
Research in my lab concerns four aspects of transcriptional regulation: histone biotinylation and gene expression; transcriptional activation and chromatin remodeling; RNA polymerase elongation factors and gene regulation; and heterochromatin and gene regulation. We use the fruit fly, Drosophila melanogaster, as a model to study mechanisms of gene activation and gene silencing.
- Different pathways to the lysosome: Sorting out alternatives.
Hasanagic M., Waheed A, Eissenberg JC. Int Rev Cell Mol Biol. (2015) 320:75-101.
- The lysosomal enzyme receptor protein (LERP) is not essential, but is implicated in lysosomal function in Drosophila melanogaster.
Hasanagic M., van Meel S., et al. Biol Open. (2015) 4:1316-1325.
- The Nobel path of cellular proteins.
Eissenberg JC, Sly WS. Mo Med. (2014) 111:114-119.
- Epigenetics: modifying the genetic blueprint.
Eissenberg JC. Mo Med. (2014) 111:428-433.
- Histone H3 lysine-to-methionine mutants as a paradigm to study chromatin signaling.
Herz, H-M, Morgan M, et al. Science. (2014) 345(6200):1065-1070.
- HP1a: A structural chormosomal protein regulating transcription.
Eissenberg JC, Elgin SC. Trends Genet. (2014) 30(3):103-110.