Tomasz Heyduk, Ph.D.
Mechanisms of transcription regulation and development of novel sensors for biomolecule detection and imaging.
Office: DRC, Room 425
Phone: (314) 977-9238
Ph.D., 1986, Technical University of Wroclaw, Poland
Our lab has two major research interests: mechanisms of transcription regulation and development of novel sensors for biomolecule detection and imaging. Our interest in transcription regulation is to understand the mechanism of transcription initiation by bacterial and archaeal RNA polymerases. Our primary focus in sensor research is to develop robust highly specific and sensitive molecular sensors that could be utilized in research, medical diagnosis and pathogen detection.
- Real-time observation of backtracking by bacterial RNA polymerase.
Lass-Napiorkowska A, Heyduk T. Biochemistry. (2016) 55(4):647-658. PubMed PMID: 26745324
- Next generation sequencing-based analysis of RNA polymerase functions.
Heyduk T, Heyduk E. Methods. (2015) 86:37-44. PubMed PMID: 25937393