Jung San Huang, Ph.D.
Novel trans-Golgi network signal transduction and autocrine transformation by the v-sis/c-sis oncogene, and the role of the transforming growth factor β (TGF-β) type V in the biological functions of TGF-β.
Office: DRC, Room 413
Voice: (314) 977-9250
Ph.D., 1972, National Taiwan University
The areas of research in this laboratory are: 1) autocrine transformation by the v-sis/c-sis oncogene and novel trans-Golgi network (TGN) signal transduction, and 2) role of the transforming growth factor ß (TGF-ß) type V receptor (TR-V) in the biological functions of TGF-ß.
- CRSBP-1/LYVE-1 ligands stimulate contraction of the CRSBP-1 associated ER network in lymphatic endothelial cells.
Hou WH, Liua IH, et al. FEBS Lett. (2012) 586(10):1480-7.
- CRSBP-1/LYVE-1 ligands disrupt lymphatic intercellular adhesion by inducing tyrosine phosphorylation and internalization of VE-cadherin.
Hou WH, Liua IH, et al. J Cell Sci. (2011) 124(Pt 8):1231-44.
- A mechanism by which dietary trans fats cause atherosclerosis.
Chen CL, Tetri LH, et al. J Nutr Biochem. (2011) 22(7):649-55.