Sergey Korolev, Ph.D.
Structure-functional studies of DNA recombination, replication and repair proteins.
Office: DRC, Room 513
Phone: (314) 977-9261
Ph.D., 1993 Engelhardt Institute of Biochemistry and Molecular Biology, Moscow, Russian Academy of Sciences
Our lab studies the mechanism of protein function at the atomic resolution level utilizing X-ray crystallography and biochemical approaches. The main focus is recombination mediator proteins (RMPs), which are essential for genome stability and DNA repair in all organisms.
- Advances in structural studies of recombination mediator proteins.
Korolev S. Biophys Chem. (2016) Dec 6 [Epub ahead of print].
- Erratum to: The loop-less tmCdc34 E2 mutant defective polyubiquitination in vitro and in vivo supports yeast growth in a manner dependent on Ubp14 and Cka2.
Lass A, Cocklin R, Scaglione KM, Skowyra M, Korolev S, Goebl M, Skowyra D. Cell Div. (2016) 11:13.
- A MUB E2 structure reveals E1 selectivity between cognate ubiquitin E2s in eukaryotes.
Lu X, Malley KR, Brenner CC, Koroleva O, Korolev S, Downes BP. Nat Commun. (2016) 7:12580.