Education
M.S., Washington University in St. Louis
Research Interests
Current goal is to lead the Center's talented and highly skilled pharmaceutical scientists to translate basic research discoveries and developed leads into viable drug candidates for neglected diseases of the poor, orphan diseases and other unmet medical needs. Some of these current targets include anti-secretory agents for the treatment of childhood diarrhea, malaria and other parasitic diseases, sickle cell disease, pulmonary fibrosis, retinopathies and TB.
Recent Publications
  • Evaluation of aminohydantoins as a novel class of antimalarial agents.
    Meyers MJ, Tortorella MD, et al. ACS Med Chem Lett. 2013 5(1):89-93.
  • Synthesis of new verapamil analogues and their evaluation in combination with rifampicin against Mycobacterium tuberculosis and molecular docking studies in the binding site of efflux protein Rv1258c.
    Singh K, Kumar M, et al. Bioorg Med Chem Lett. 2014 24(14):2985-2990.
  • Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs.
    Henderson NC, Arnold TD, et al. Nat Med. 2013 19(12):1617-1624.