A shared-use facility that supports expression, purification, and analysis of research proteins by providing an array of instrumentation and consultation on strategies for protein production from small to large scale.
For a complete description of all available services, please see the Protein Core website.
A state-of-the-art X-ray facility is available to researchers in the department for the collection of high-resolution data on macromolecular samples. The facility has a 0.8 kW MM007 Rigaku generator with VHF optics interfaced to an R-Axis IV++ imaging plate system and a 1.2 kW MM007HF Rigaku generator with VHF optics double ported with two R-Axis IV++ imaging plate systems. A Phoenix robotic instrumentation from Art Robbins Instruments is available for the preparation, screening and imaging of crystals.
The Department of Biochemistry and Molecular Biology maintains a wide variety of computing resources. These range from network and backup services to state-of-the-art high performance computing.
The most recent addition to the department is the Gemini Computing Cluster, a state-of-the-art, high performance computing cluster, leveraging modern technologies such as GPU computing capabilities. You can find out more information on the Gemini website.
State-of-the-art differential scanning and isothermal titration calorimeters are available to researchers in the department to study protein stability and the thermodynamic components of protein-protein, protein-ligand and protein-nucleic acids interactions. These instruments include a MicroCal iTC200 microcalorimeter for isothermal titration studies and a MicroCal VP-DSC for differential scanning calorimetry.